Greens losing gene battle

Are we losing the TB battle?

Internal network dynamics prolong a losing battle

Fights-to-the-death occur in many natural, medical and commercial settings. Standard mass action theory and conventional wisdom imply that the minority (i.e. smaller) group’s survival time decreases as its relative initial size decreases, in the absence of replenishment. Here we show that the opposite actually happens, if the minority group features internal network dynamics. Our analytic theor...

Is INH waging a lonely losing battle.

The Updated National Guidelines for Pediatric Tuberculosis in India, 2012, [1] has rightly emphasized, at length, the need for becoming more aggressive in our treatment of pediatric tuberculosis (dropping out 3 drugs from all regimens i.e. HRZ). The area of chemoprophylaxis, however, has been left untouched [except for raising the dose of INH to 10 mg/kg/day). We all know and accept that resist...

Obesity Research: Winning the Battle, Losing the War

Diabetes and obesity have increased dramatically in the United States during the past quarter century and are having a profound, negative impact on morbidity, mortality, quality of life, and cost of medical care. New research confirms that diabetes can be prevented or delayed through aggressive weight management. After years of discouraging reports on the failure of weight management programs t...

A losing battle: weight regain does not restore weight loss-induced bone loss in postmenopausal women.

Previously, we reported significant bone mineral density (BMD) loss in postmenopausal women after modest weight loss. It remains unclear whether the magnitude of BMD change in response to weight loss is appropriate (i.e., proportional to weight loss) and whether BMD is recovered with weight regain. We now report changes in BMD after a 1-year follow-up. Subjects (n = 23) in this secondary analys...